منابع مشابه
Return of the Electric Binding Site
The BK-type Ca 2+-activated K + channel has been the subject of increasingly detailed mechanistic study since the fi rst recordings of this channel were obtained more than 25 years ago (Pallotta et al., 1981 ; Latorre et al., 1982 ; Magleby, 2003 ; and references therein). But if you thought that our understanding of the gating of the BK channel and its allosteric regulation by Ca 2+ and trans-...
متن کاملcontribution of setting to the study of characters and the main idea in e. brontes: wuthering heights and t. hardys: return of the native.
this thesis aims to adduce an unmitigated and comprehensive explication concerning the relationship of three significant elements of fiction: setting, chracter and theme. my research is basically placed on two outstanding novels of the 19th century: emily brontes wuthering heights and thomas hardys return of the native. my endeavour lies in studying the correlation among the three above-mention...
15 صفحه اولInvestigation and Determination the Binding Site of Glycyrrhizin of Liquorice to DNA
Glycyrrhizin(GL), is a triterpenoid saponin found in glychyrrhiza glabra (liquorice). This compound is a frequently used and very effective drug for the treatment of various malignancies. This study was designed to examine the interactions of glycyrrhizin with calf thymus DNA in aqueous solution at physiological conditions. FTIR spectroscopic method was used to determine the ligand binding mode...
متن کاملIn silico Study of Toll-Like Receptor 4 Binding Site of FimH from Uropathogenic Escherichia coli
Introduction : The innate immune system as the first line of defense against the pathogens recognizes pathogen-associated molecular patterns (PAMPs) by Toll-Like Receptors (TLRs). Interaction of bacterial PAMPs by TLRs results in activation of innate and acquired immunity. FimH adhesin, a minor component of type 1 fimbriae encoded by Uropathogenic Escherichia coli (UPEC) is a PAMP of TLR4 tha...
متن کاملInvestigating Dynamic Properties of Residues of Warfarin-Azapropazone Binding Site in Human Serum Albumin
Introduction: Human Serum Albumin (HSA) is one of the most important proteins in blood that can bind a wide range of components and different drugs such as Warfarin and is also circulated in the body by HSA. Therefore, studying HSA is very significant in pharmacology. In this research, dynamic behavior of residues of Warfain binding site of HSA has been investigated. Methods: Firstly, PDB form...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 2008
ISSN: 1540-7748,0022-1295
DOI: 10.1085/jgp.200810135